WHAT ARE TELOMERES?

Telomeres are segments of DNA at the end of our chromosomes. Scientists frequently compare them to the plastic tips of shoelaces that keep the laces together. Telomeres function similarly, preventing chromosomes from fraying or tangling with one another. When that happens, it can cause genetic information to get mixed up or destroyed, leading to cell malfunction, increasing the risk of disease or even shortening lifespans.

Each time a cell divides, its telomeres become shorter. After years of splicing and dicing, telomeres become too short for more divisions. At this point, cells are unable to divide further and become inactive, die or continue dividing anyway -an abnormal process that’s potentially dangerous.

What is Telomerase?

Telomerase is an enzyme that plays a vital role in maintaining the length of telomeres and aids in stabilizing chromosomes during cell division. But with constant cell division, telomerase levels are depleted, enabling telomeres to shorten.  In the presence of telomerase, dividing cells can replace lost bits of DNA and even repair the cells to allow the process of healthy cell division to continue. Telomeres would thus remain long, lengthening life spans and possibly reducing the risk of some diseases.

 

Diseases related to short telomeres

    • People who are suffering from cardiomyopathy, a form of heart disease, have abnormally short telomeres in their heart muscle cells.

    • Muscular dystrophy, when stem cells in the muscle are unable to regenerate new muscle, is due to shortened telomeres

    • Type 2 diabetes is associated with DNA damage which is hypothesized to be the result of telomere shortening.

    • Osteoporosis is associated with shorter telomeres.

    • Measuring telomere length can help with treatment decisions for patients with certain types of bone marrow dysfunction.

    • In a study of 143 individuals over 60, those with shorter telomeres were three times more likely to die from heart disease.

    • Skin and mucosal abnormalities – In dyskeratosis congenita, patients’ skin may have abnormal pigmentation, with a lack or overabundance of spots and patches. The pigmentation pattern typically appears on sun-exposed areas of the face, neck and upper trunk. Other symptoms can include hair graying at a young age and nail weakness or splitting along with ridging.

 


Why It’s So Important To Keep Your Telomeres Long

Your telomeres start shortening even before you are born. They keep shortening throughout your life. By the time you’re middle-aged, your telomeres are dramatically shorter. And this is not good news for your health.

It means your cells are becoming less functional and less capable of repairing themselves. Shorter telomeres increase the chance that your cells become old and dormant. Almost like “zombie” cells.

So slowing down the shortening of your telomeres may be helpful in supporting healthy aging at the cellular level.

Supplements that support telomere health typically boost or protect telomerase (DNA Telomere Formula), the enzyme that protects telomeres. Telomeres, in turn, protect dividing cells from DNA damage. Supplements that support mitochondrial function (DNA Mito-Choice) typically provide energy and improve mood while protecting against mitochondrial-induced cell death and aging.

Like other kinds of cells, immune cells lose their ability to divide over time as the telomeres on their chromosomes become progressively shorter with each cell division. As a result, the disease-fighting ability of immune cells becomes compromised with age. In the new study the team at UCLA found that the compound, cycloastragenol, derived from Chinese Astragalus root, can prevent or slow the progressive loss of telomeres in key immune cells, potentially making it a key weapon in the fight against HIV and other viral diseases.

Natural antioxidants for optimal telomere protection
DNA Telomere Formula contains powerful natural antioxidants, the activity of which curbs the shortening of telomeres by protecting them from oxidative stress, a process known to contribute to cellular ageing. To combat oxidative stress, maintain telomere length and thus protect DNA, the following herbal extracts have been synergistically combined in DNA Telomere Formula : Terminalia chebula, Astralagus, Rhodolia, N Acetyl-Cysteine, Broccoli Sprout Extract and Alpha Lipoic Acid. which contains tannins with antioxidant and cytoprotective effects. 

 The combination of these herbal extracts in a single capsule means this supplement offers the following benefits:

- telomere protection from powerful natural antioxidants;
- reactivation of telomerase via the activity of certain bioactive compounds.

Natural extracts to reactivate telomerase
In addition to protecting telomeres, DNA Telomere Formula reactivates telomerase. Considered the ‘immortality enzyme’, telomerase counteracts telomere shortening. This enzyme, the discovery of which was rewarded with a Nobel Prize in 2009, halts the cellular ageing process by repairing telomeres and ensuring their growth. Given its key role in longevity, this enzymatic activity needs to be maintained throughout life. 

 The combination of these herbal extracts in a single capsule means this supplement offers the following benefits:

- telomere protection from powerful natural antioxidants;
- reactivation of telomerase via the activity of certain bioactive compounds.