What causes infections to subside for awhile but then reappear?

Bacterial and fungal biofilms might be to blame.

Biofilms are formations that occur when a group of microorganisms such as bacteria, fungi, parasites and viruses attach themselves to a surface and create a colony. A biofilm is formed and maintained via cell-to-cell communication. A biofilm first forms when one or a few cells attach to a surface. These first cells produce proteins that act as signals to nearby cells. The signals are detected by neighboring cells and essentially recruit new cells into the colony. As the nearby cells detect the chemical cues they aggregate and begin to form the biofilm. These cells then send out additional signals, recruiting more cells to the colony and growing the biofilm. The proteins also signal the development of polysaccharides that will form the slime layer. This slime layer forms over and around the growing colony.These biofilms form themselves into a type of ‘shield’ that has a glue-like consistency, often referred to as ‘slime’. Biofilms then act as a barrier and help the colony to defend itself against antimicrobial treatments and our immune cells.
Biofilms can be the reason that some wounds may be difficult to heal, and why persistent infections may keep recurring. 

 

WHERE ARE BIOFILMS FOUND?
A biofilm colony secretes material that provides a structural matrix, similar to cement. These structures can adhere to surfaces such as the lining of the gastrointestinal tract, (The GI tract is an ideal environment for bacteria, fungi, and associated biofilms because of its huge surface area and constant influx of nutrients. For protection, the GI epithelium is lined with viscoelastic mucus, but it can be damaged in patients with excessive inflammation, irritable bowl disease, and other conditions. This creates an opportunity for bacteria to attach to the surface and begin their biofilm construction. The epithelium to which it is attached is altered and often damaged) urinary tract, respiratory system, heart, mouth (including the teeth), sex organs, eyes, the middle ear and skin.
Biofilms can also form on medical materials such as catheters, joint replacements, heart valves and they commonly occur in hospital environments.

BIOFILMS ARE GOOD AT ‘HIDING’ MICROBES
Up to 80% of infections in the body affecting the body systems mentioned above are associated with biofilm formation. Once formed, these biofilms can make it challenging for antimicrobial treatments to penetrate the biofilm. A microbial biofilm is continuously changing, stimulating inflammation, and acting as an obstacle for the action of the immune system. These types of persistent infections may be correlated to a range of health complaints including middle ear infections, urinary tract infections, gastro-intestinal infections, fungal overgrowth (candida) and more. Antibiotics cause massive damage to your gut and mitochondria. They should be your last resort for dealing with an infection. But sometimes antibiotics really are the best course of action, and at those times, serrapeptase benefits you by making antibiotics more effective. It weakens the biofilms around antibiotic-resistant bacteria, making them more susceptible to antibiotics.

 

Serra-Fast Capsules in the removal of Biofilm.
Serra-Fast contains the following ingredients which are effective in removing and contrlling Biofilm.
Serrapeptase
Serrapeptase is a strong antimicrobial. It weakens biofilms around antibiotic-resistant bacteria, which can make it a great way to get rid of pathogens. Serrapeptase is effective for eradicating infection caused by biofilm-forming bacteria. The antibiofilm property of the enzyme enhances antibiotic efficacy in the treatment of staphylococcal infections. (ref The effect of proteolytic enzyme serrapeptase in the treatment of experimental implant-related infection.) Antibiotics cause massive damage to your gut and mitochondria. They should be your last resort for dealing with an infection. But sometimes antibiotics really are the best course of action, and at those times, serrapeptase benefits you by making antibiotics more effective. It weakens the biofilms around antibiotic-resistant bacteria, making them more susceptible to antibiotics. For bacteria that create protein-dependent biofilms, it appears that serrapeptase may have an inhibitory effect on biofilm production.

Brahmi
In a study to evaluate the antibiofilm and antimicrobial activities of Brahmi against Staphylococcus aureus and Pseudomonas aeruginosa, which are known to form biofilms as one of their virulence traits. Bacoside A showed antimicrobial activity against both test organisms in their planktonic and biofilm states and significantly removed 88%-93% of bacterial biofilm developed on microtiter plates. These results indicate that Brahmi might be considered as an antimicrobial having the ability to disrupt biofilms and could be useful to treat biofilm-related infections caused by opportunistic bacterial pathogens.

 

Curcumin
A 2014 study review acknowledged curcumin as an effective anti-bacterial, anti-fungal, anti-viral, as well as anti-parasitic. On top of the anti-pathogen benefits, curcumin has also been deemed significantly effective at disrupting biofilm. 
Another 2013 study found that out of 35 different compounds observed, curcumin landed itself as one of the top six biofilm-disrupting agents.

 

MSM
Helps the body dispose of the biofilm.